Hydrocodone is a type of opioid, like heroin, but doctors can legally prescribe it for moderate-to-severe pain. Since it is classified as an opioid, there is the potential for dependence, abuse, and addiction to this drug. This can happen whether it is legally or illegally obtained.
Like any drug, hydrocodone has to be processed out of the body. How long it stays in a person’s system varies according to a range of factors.
As an opioid, hydrocodone results in physical dependence if taken for a sustained period. This dependence can form relatively quickly, often in a matter of weeks. Once dependence has taken hold, withdrawal symptoms will appear as the drug begins to leave the body. Since these symptoms are uncomfortable, they often motivate continued use to keep them at bay.
It is possible to start experiencing withdrawal symptoms within eight hours to 24 hours after someone stops taking hydrocodone, according to Clinical Guidelines for Withdrawal Management and Treatment of Drug Dependence in Closed Settings. Once withdrawal starts, people often experience the effects for up to 10 days.
The following may be experienced:
Ready to get help?
Give us a call.
Because of the challenges of the withdrawal process, it is recommended that people undergo withdrawal at a detox facility. A medically supervised detox program can help people to be more comfortable as they get the hydrocodone out of their system. This increases the likelihood that they will complete withdrawal and avoid overdose or relapse. Medications are often used in medical detox programs.
The exact length of time this drug stays in someone’s system ultimately depends on several factors. Among them are:
Generally, the pain relief effects of hydrocodone can be felt for four to six hours. The drug and its metabolites remain in the body even after the effects have worn off, however.
Different types of drug tests can detect hydrocodone for varying amounts of time.
Hydrocodone tends to stay in a person’s hair the longest. On average, hair testing can detect the presence of hydrocodone for about 90 days, according to information presented by Drug and Alcohol Dependence.
The other ways to test for hydrocodone usually cannot detect this drug for as long because it has a short half-life. For example, if someone submits to saliva testing, this test can only detect the presence of hydrocodone for about 12 hours to 36 hours.
Hydrocodone may stay in the urine for two to four days, according to the Substance Abuse and Mental Health Services Administration. In most cases, when a test is done for hydrocodone, it is urine that is used to look for the presence of this drug.
Blood tests are generally not used to look for hydrocodone in the body. This is because they are largely unreliable since the drug’s half-life is so short.
People who plan to go to a treatment facility for hydrocodone abuse or addiction will usually take a drug test when they start the intake process. It is common for additional testing to be administered throughout the program to ensure the person is staying sober.
Again, hydrocodone affects different people differently, so the amount of time it stays in a person’s system will vary. Likewise, the dosage that will trigger an overdose will vary from person to person.
If someone mixes hydrocodone with another substance of abuse, there is a higher chance that they will experience an overdose. In particular, using hydrocodone with alcohol, benzodiazepines, or other opiates further increases the risk of overdose since all of these substances can result in respiratory depression. As a result, it is possible for someone to stop breathing during an overdose.
When the brain does not get enough oxygen, it can result in severe injury. In mild cases, people can experience cognitive function issues and motor coordination problems. In severe cases in which a person’s brain went without oxygen for a longer time, seizures, coma, and brain death may result, according to the National Institute of Neurological Disorders and Stroke.
Other overdose symptoms include:
The dose needed to overdose on hydrocodone depends on several factors, such as how often the person uses opioids and their metabolism. The research into the dose that can cause overdose has not discovered a single number. However, one study discovered that 0.47 mg/L (milligrams per liter) as the average hydrocodone concentration resulted in death, according to research published in the American Journal of Forensic Medicine and Pathology.
Any person who thinks they might have developed an addiction to hydrocodone should seek help from a treatment facility. In recovery, you won’t have to worry about possibly failing drug tests. You can enjoy a safe, balanced life of sobriety.
Hydrocodone is a prescription medication that people sometimes abuse. Because it is an opiate, it can produce a sense of euphoria that people seek when they use the medication to get high.
When people take this medication, it is possible to experience side effects that may include the following:
The half-life of hydrocodone is about four hours, according to the U.S. Food and Drug Administration. The half-life is how long it takes the body to remove half of the dosage. For example, if someone takes 10 mg (milligrams) of hydrocodone, after four hours, about 5 mg of the drug has been removed from the body. When someone takes a dose of hydrocodone orally, they typically start to experience the effects within 30 minutes.
(July 2011) What is the Lethal Concentration of Hydrocodone? A Comparison of Postmortem Hydrocodone Concentrations in Lethal and Incidental Intoxications. American Journal of Forensic Medicine and Pathology. from https://www.ncbi.nlm.nih.gov/pubmed/20407360
Vicodin. Food and Drug Administration. from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/088058s027lbl.pdf
(August 2014) Hair Drug Testing Results and Self-Reported Drug Use Among Primary Care Patients with Moderate-Risk Illicit Drug Use. Drug and Alcohol Dependence. from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080811/
Hydrocodone. MedlinePlus. from https://medlineplus.gov/druginfo/meds/a614045.html
Hydrocodone/Oxycodone Overdose. MedlinePlus. from https://medlineplus.gov/ency/article/007285.htm
Cerebral Hypoxia Information Page. National Institute of Neurological Disorders and Stroke. from https://www.ninds.nih.gov/Disorders/All-Disorders/Cerebral-Hypoxia-Information-Page
Withdrawal Management. Clinical Guidelines for Withdrawal Management and Treatment of Drug Dependence in Closed Settings. from https://www.ncbi.nlm.nih.gov/books/NBK310652/
Tapering Off Opioids: When and How. Mayo Clinic. from https://www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/in-depth/tapering-off-opioids-when-and-how/art-20386036
Oxycodone and Hydrocodone: Detection in Urine, Oral Fluid, and Blood. Substance Abuse and Mental Health Services Administration. from https://www.samhsa.gov/sites/default/files/meeting/documents/flegel-research-studies-dtab-june-2014_0.pdf